20+
Peer-Reviewed Publications
Molecular Genetics & Nanotechnology · MCARS, Jamia Millia Islamia
Where molecular genetics meets nanotechnology to outpace antimicrobial resistance.
JoshiTxDx Lab builds next-generation therapeutics (Tx) and diagnostics (Dx) — from phage therapy to gold-nanoconjugate detection — grounded in the science of how resistance evolves.
Funded by
DBT–Wellcome India AllianceSERBICMR
Signature platform
Gold-nanoconjugate biosensor — fluoresces on binding DNA damage
Gold + RecA probelabel-free conjugate
Readoutfluoresces on binding
Tx
Dx
Nanoparticle
24
Researchers Trained
04
Patent Filings · IN + EU
04
Major Research Grants
Research
Three fronts against antimicrobial resistance
Treat resistant infection, detect it, and understand how it evolves. Each front links to the full detail.
Tx · Therapeutics
Phage therapy
Lytic bacteriophage cocktails against multidrug-resistant ESKAPE pathogens — biological alternatives to antibiotics.
How it works →Dx · Diagnostics
Gold nanoconjugates
Functionalised gold-nanoparticle platforms for ultra-sensitive, label-free detection of pathogens and DNA damage.
How it works →BS · Basic Science
Genome stability
Chromosome cohesion and DNA double-strand-break repair in E. coli — the science beneath Tx and Dx.
How it works →Open to research & clinical collaboration
Working on resistance, diagnostics, or genome stability — or looking for a PhD in the area? Let’s talk.
The people
Led by Dr. Mohan C. Joshi
Dr. Mohan C. Joshi
Principal Investigator · Assistant Professor (UGC-FRP)
Molecular genetics and nanotechnology, aimed at the antimicrobial-resistance crisis. Ph.D. from JNU; postdoctoral training at Baylor College of Medicine.
Shabina
Amir
Nuha
Naima
Ifra
Hamna
Selected publications
Peer-reviewed, DOI-linked
A few flagship papers — the full record, browsable by theme and explained for every kind of reader, lives on the Publications page.
Khan NA, Khan T, Islam A, Joshi MC. Live-Cell Visualization of DNA Double-Strand Break Repair Dynamics via Recombinase-Coated Gold Nanoconjugates.doi.org/10.1021/acsanm.6c02832
ACS Appl. Nano Mater. · 2026
Faraz A, Khan NA, Singh DK, Joshi MC. Loss of SeqA Confers Low-Level Fluoroquinolone Resistance Through Transcriptional Reprogramming and RpoS Dependence in E. coli.doi.org/10.3934/microbiol.2025047
AIMS Microbiology · 2026
Xia J, … Joshi MC, … Rosenberg SM. Bacteria-to-Human Protein Networks Reveal Origins of Endogenous DNA Damage.doi.org/10.1016/j.cell.2018.12.008
Cell · 2019
Quadir S, Khan NA, Singh DK, Faraz A, Jhingan GD, Joshi MC. Exposure to High Dosage of Gold Nanoparticles Accelerates Growth Rate by Modulating Ribosomal Protein Expression.doi.org/10.1021/acsnano.3c01973
ACS Nano · 2023
Joshi MC, Bourniquel A, … Kleckner N, Bates D. E. coli sister chromosome separation includes an abrupt global transition…doi.org/10.1073/pnas.1019593108
PNAS · 2011
Azmi I, Faizan MI, … Joshi MC*, Ahmad T*. A Saliva-Based RNA Extraction-Free Workflow Integrated With Cas13a for SARS-CoV-2 Detection.doi.org/10.3389/fcimb.2021.632646
Front. Cell. Infect. Microbiol. · 2021
Recognition
Funded by DBT–Wellcome India Alliance, SERB and ICMR. Three competitive national fellowships (India Alliance · Ramanujan · Ramalingaswami), four patent filings, and 20+ peer-reviewed papers.
From the lab
Reflections
Plain-language notes from Dr. Joshi on new work, talks, and where the field is heading.
Three currents in phage therapy I brought home.
Where clinical phage work is quietly maturing — and where the field still disagrees.
Reading DNA damage without touching the genome.
Our RecA-nanoconjugate approach, explained for a non-specialist.
The AMR numbers that should reorder our priorities.
What recent surveillance data changes for a lab like ours.
Connect with the lab
Collaborate, cite, or reach out
- Institutional home
- Multidisciplinary Centre for Advanced Research and Studies (MCARS)
Jamia Millia Islamia · Jamia Nagar, New Delhi – 110025, India - Scholarly identity
- ORCID · Google Scholar · ResearchGate (linked in the footer)
For research or clinical collaboration, PhD and training enquiries, or press. Send a note — it reaches the lab directly.